The 2025 SAG Awards last night set social media alight with fans shocked by several actresses who showcased remarkably slimmer figures on the red carpet.
Users were quick to highlight one strikingly similar physical feature among the A-listers gathered in Los Angeles — their ’emaciated’ arms.
‘Arms are looking crazy and the dress isn’t helping’, one said, commenting on pictures of glamorously dressed actress Demi Moore.
‘There’s thin and then there’s emaciated and gaunt,’ shot back another.
‘There needs to be like some sort of preventative measure against clearly malnourished and starved celebrities being allowed to flaunt their bodies on red carpets like this,’ a third argued.
Now, experts have sounded the alarm over the unwanted consequence — dubbed ‘Ozempic arms’ — which they believe may be a side effect of weight loss jabs, collectively known as GLP-1 agonists.
Professor Alexander Miras, an obesity treatment expert at Imperial College London, told MailOnline: ‘It’s another consequence of the injections.
‘It’s similar to what has been been seen before with Ozempic face and Ozempic butt.
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Moore has been accused of using Ozempic after showing off a notably slimmer frame recently while on the promo tour for The Substance (right, in 2021)
‘Arms are looking crazy and the dress isn’t helping’, one said, commenting on picturs of glamorously dressed actress Demi Moore
Georgina Chapman displayed her slimmer figure in a black gown (right, in 2022)
‘It’s not an effect of the drug itself, but caused by the dramatic weight loss it can trigger. This removes fat from below the skin.’
It is most apparent at joints such as the elbow where there is little muscle mass, meaning skin will stretch and sag more easily, he said.
If the drugs are ‘abused’ by people who are not overweight—in order to stay extremely thin—the effect can be even more dramatic, Prof Miras added.
‘But, the younger someone is, the more likely it is that their skin can improve because it’s more elastic and is more likely to adapt to the new weight over time,’ he added.
One US-based plastic surgeon, even said the skin quality of some of his patients on GLP-1s has reminded him of ‘an old, overused rubber band’.
Dr Julius Few, who works in Chicago and Beverly Hills estimates that about 25 to 30 percent of his patients are currently taking a GLP-1, which ‘almost seems to age the quality of the skin, like the skin takes on an appearance of an older person’.
Experts have long warned of the risks of rapid loss of muscle mass while on the drugs.
And last month singer Avery revealed she had developed bone-thinning disease osteoporosis — a condition that puts sufferers at high risk of deadly fractures — after ‘losing too much weight’ on Ozempic.
Brook Shields revealed a svelte new look, including dramatically slender arms, while Ariana Grande’s thin frame has sparked concern among fans recently
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Last year, TV personality Sharon Osbourne also confessed she lost ‘almost half’ her body weight and ‘had flesh hanging everywhere. My breasts were flat and sagging’.
Professor Miras said: ‘The problem is that there isn’t much that people can actually do to counteract the issue apart from physical activity and weight training the part of the body, like the upper arms, that needs to build up the muscle.
‘In more extreme cases people have had plastic surgery.
He added: ‘But users with smaller BMIs that take the drugs are putting themselves at risk of worsening their appearance for no reason.
‘The issue really is that this medication is not for people who just want to look better. This is not a cosmetic drug.
‘These are medications for people who have obesity and are also living with the complications of the disease.
‘We want people who have diabetes or who have high blood pressure or sleep apnea to be using those medications because then any cosmetic side effects of the medications may be worth their while because of the health benefits.’